http://journalarrb.com/index.php/ARRB/issue/feed Annual Research & Review in Biology 2019-11-15T05:21:51+00:00 Annual Research & Review in Biology contact@journalarrb.com Open Journal Systems <p style="text-align: justify;">The aim of <strong>Annual Research &amp; Review in Biology (ARRB)</strong> <strong>(ISSN: 2347-565X)</strong> <strong>(Previous name:</strong> <strong>Annual Review &amp; Research in Biology, ISSN: 2231-4776</strong>) is to publish high quality papers (<a href="/index.php/ARRB/general-guideline-for-authors">Click here for Types of paper</a>) with broad areas of Aerobiology, &nbsp;Agriculture, Anatomy, Astrobiology, Biochemistry, Bioengineering, Bioinformatics, Biomathematics or Mathematical Biology, Biomechanics, Biomedical research, Biophysics, Biotechnology, Building biology, Botany, Cell biology, Conservation Biology, Cryobiology, Developmental biology, Food biology, Ecology, Embryology, Entomology, Environmental Biology, Epidemiology, Ethology, Evolutionary Biology, Genetics, Herpetology, Histology, Ichthyology, Integrative biology, Limnology,&nbsp; Mammalogy, Marine Biology, Microbiology, Molecular Biology, Mycology, Neurobiology, Oceanography, Oncology, Ornithology, Population biology, Population ecology, Population genetics, Paleontology, Pathobiology or pathology, Parasitology, Pharmacology, Physiology, Psychobiology, Sociobiology, Structural biology, Virology and&nbsp; Zoology. This is a quality controlled, peer-reviewed, open access INTERNATIONAL journal.</p> http://journalarrb.com/index.php/ARRB/article/view/30131 The High Water Plants Water Road in Cleaning 2019-11-15T05:21:51+00:00 Ch. H. Kuchkarova Cholpanoy89@mail.ru U. S. Nizamova Sh Abdullaev G. A. Madrakhimova <p>The ecology of high-water plants such as pistachio, euchronia, azolla forms the basis for improving biological wastewater treatment technology. For the first time in the Andizhan region of the Republic of Uzbekistan, it was found that high-altitude algae can be used by the method of biological treatment of municipal wastewater. the results of the study, we used biological treatment of high-water plant species such as pistia (Pistia stratiotes), Euchornia crassipes Solms, azolla (Azolla coroliniana Willd), with the observations of the dynamics of rapid growth and development at high concentrations. We developed a Pistia stratiotes, which is scientifically grounded in improvement, and was recommended for reproduction under laboratory conditions.</p> 2019-11-08T00:00:00+00:00 ##submission.copyrightStatement## http://journalarrb.com/index.php/ARRB/article/view/30132 Prevalence of Sickle Cell Disease and Other Haemoglobin Variants in Calabar, Cross River State, Nigeria 2019-11-15T05:21:50+00:00 Akaba Kingsley akaba_kingsley@yahoo.com Ofem Enang Ofonime Essien Annette Legogie Omini Cletus Olukayode Oshatuyi <p><strong>Background: </strong>Sickle cell disease (SCD) is the commonest genetic disorder worldwide with a global prevalence of 20-25 million. About 12-15 million affected persons are in Sub-Sahara Africa with Nigeria bearing the highest burden of people living with sickle cell disease. SCD is a disease characterized as an autosomal, recessive, heterogeneous, and a monogenetic disorder caused by an A-to-T point mutation in the β-globin gene responsible for the production of abnormal hemoglobin S (HbS), which polymerizes in the deoxygenated state and results in the sickling of erythrocytes.&nbsp; Haemoglobin variants are mutant forms of haemoglobin in a population usually occurring as a result of genetic changes in specific genes, or globins that causes change on alterations in the amino acid. They could affect the structure, behavior, the production rate and the stability of the specific gene. Well-known haemoglobin variants such as sick-cell anaemia are responsible for diseases and are considered haemoglobinopathies. Other variants cause no detectable pathology and are thus considered as non-pathological variants.</p> <p><strong>Aim: </strong>The study is aimed at evaluating the burden of sickle cell disease and other haemoglobin variants in Calabar, South-South Nigeria.</p> <p><strong>Methods: </strong>This is a retrospective study done at the haematology laboratory of University of Calabar Teaching Hospital, Calabar. Cellulose acetate electrophoresis at alkaline pH was used for the evaluation of haemoglobinopathies. The data were entered into Microsoft Excel 2016 spreadsheet and analysed with the IBM SPSS Version 22. Data were summarized into percentage of different phenotypes.</p> <p><strong>Results: </strong>Results of the total 3648 haemoglobin electrophoresis recorded, 1368 (37.50%) were male while the remaining 2280 (62.5%) females given a male to female ratio of 1:1.7. Five haemoglobin phenotypes were identified as HbAA, HbAS, HbAC, HbSC and HbSS. The overall average values of their prevalence were HbAA 64.78%, HbAS 32.62%, HbSS 2.14%, HbAC 0.33%, HbSC 0.14%. Thus, the prevalence of SCD (Prevalence of HbSS+HbSC) was 2.28%. The highest proportion of SCD was observed in 2011 with least in 2016 and 2017 respectively.</p> <p><strong>Conclusion: </strong>The prevalence of SCD and other haemoglobin variants in Calabar is similar to that of the national prevalence rate. There is need for continuous enlightenment and premarital counselling on the pattern of inheritance of SCD most especially with the increased burden of sickle traits in the environment has reported in this study.</p> 2019-11-13T00:00:00+00:00 ##submission.copyrightStatement##