Epidemiology, Treatment and Microbiological Surveillance of SARS-CoV-2
Annual Research & Review in Biology,
Page 114-121
DOI:
10.9734/arrb/2020/v35i530230
Abstract
Coronaviruses (CoV) belong to Coronaviridiae family that cause deadly diseases in humans or animals. These viruses are enveloped and have single stranded positive-sense large RNA genome. Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) causes deadly pandemic coronavirus disease-2019 (COVID-19) in humans. It is affecting every aspect of humans’ daily life. The symptoms of COVID-19 include fever, loss of smell, shortness of breath, cough, muscles pain, chest pain, and kidney failure that occurs in severe conditions. The virus has spread throughout the world. In India, the estimated number of infected people is more than 1.5 lakh with less fatality rate 2.87% on May 27, 2020 as per the Ministry of Health and Family Welfare data. The studies suggest that virus has been considered descended from the previous viruses as severe acute respiratory syndrome corona virus (SARS-CoV), Middle East respiratory syndrome virus (MERS) human and bat corona viruses. Currently, vaccine developments are under clinical trials. The management of emerging infectious diseases is a challenging task. It requires much improved microbiological surveillance system to track and predict the virus infections. The proper study and predictions based on screening of various sources of infection may help us to manage the challenging infections in future. The present review summarizes the characteristics of virus, disease symptoms, epidemiology, transmission, treatment and microbiological surveillance of pandemic COVID-19.
Keywords:
- Coronavirus
- COVID-19
- microbiological surveillance
- pandemic
- SARS-CoV-2
How to Cite
Tripathi, M., & Kumar, S. (2020). Epidemiology, Treatment and Microbiological Surveillance of SARS-CoV-2. Annual Research & Review in Biology, 35(5), 114-121. https://doi.org/10.9734/arrb/2020/v35i530230
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DOI:https://doi.org/10.1016/ S0140-6736(20)30251-8
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DOI:https://doi.org/10.1007/978-1-4939-7_1
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DOI: 10.1128/JVI.01504-18
Alvaro D, Branch E, Challener CA.
Available:https://www.pharmasalmanac.com/articles/covid-19-a-look-at-the-virus-its-epidemiology-therapeutic-and-vaccine-development-efforts-and-impacts-of-the-pandemic)
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DOI: 10.1155/2011/734690
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DOI: 10.1038/d41573-020-00073-5
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DOI: 10.1016/j.phrs.2020.104859
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Lin SC, Ho CT, Chuo WH, et al. Effective inhibition of MERS-CoV infection by resveratrol. BMC Infect Dis. 2017; 17(1):144.
DOI:https://doi.org/10.1186/s12879-017-2253-8
Kampf G, Todt D, Pfaender S, et al. Persistence of coronaviruses on inanimate surfaces and their inactivation with biocidal agents. J Hospial Inf. 2020;104:246-251.
DOI: https://doi.org/10.1016/j.jhin.2020.01.022
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DOI: 10.14744/ejmo.2020.87844
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DOI:10.14744/ejmo.2020.72142
Kumar V, Dhanjal JK, Kaul SC, et al. Withanone and caffeic acid phenethyl ester are predicted to interact with main protease (Mpro) of SARS-CoV-2 and inhibit its activity. J Biomol Stru Dyn; 2020.
DOI:https://doi.org/10.1080/07391102.2020.1772108
Li X, Geng M, Peng Y, et al. Molecular immune pathogenesis and diagnosis of COVID-19. J Pharm Anal. 2020;10:102-108.
DOI:https://doi.org/10.1016/j.pha.2020.03.001
Gupta N, Potdar V, Praaraj I, et al. Laboratory preparedness of SARS-CoV2 testing in India: harnessing a network of virus research and diagnostic laboratories. Indian J Med Res; 2020.
DOI: 10.4103/ijmr.IJMR_594_20
Loeffelholz MJ, Tang Y-W. Laboratory diagnosis of emerging human coronavirus infections–the state of the art. Emerg Infect Dis. 2020;9:747-756.
DOI: 10.1080/22221751.2020.1745095
Yadav P, Shete-Aich A, Nyayanit DA, et al. Detection of coronaviruses in Pteropus & Rousettus species of bats from different States of India. Indian J Med Res; 2020.
DOI: 10.4103/ijmr.IJMR_763_20
Mourya DT, Sapkal G, Yadav PD, et al. Biorisk assessment for infrastructure & biosafety requirements for the laboratories providing coronavirus SARS-CoV-2/(COVID-19) diagnosis. Indian J Med Res; 2020.
DOI: 10.4103/ijmr.IJMR_763_20
Hafeez A, Ahmad S, Siddqui S, et al. A review of COVID-19 (coronavirus disease-2019) diagnosis, treatments and prevention. EJMO. 2020;4(2):116-125.
DOI: 10.14744/ejmo.2020.90853
Available:https://www.who.int/southeastasia/outbreaks-and-emergencies/novel-coronavirus-2019/protective-measures
(Accessed on 31 March, 2020)
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