Neoplasias in Fish: Review of the Last 20 Years. A Look from the Pathology
Annual Research & Review in Biology,
Page 134-153
DOI:
10.9734/arrb/2020/v35i1230319
Abstract
In fish there is an innumerable variety of neoplasias that arise essentially from all cell types. Neolasia here, we will focus on the neoplasias that appear spontaneously in these animals and will not cover the experimentally induced neoplasias and/or the animal models of neoplasias. As for diagnosis, in general, specialists in aquatic organism pathology are not so familiar with the diagnosis of neoplasias. Infectious pathology, as opposed to non-infectious pathology, is the predominant condition in this area and, of course, these are of greater importance because some infectious diseases generate great economic losses, while neoplasias are isolated pathologies, with some exceptions.
In the last 20 years, 10 neoplasias in different species have been diagnosed in our laboratory, and we reported their characteristics in this paper. We also made a detailed bibliography review and observed how 90 neoplasias among 56 species of teleosteal fish were reported.
Neoplasias in fish, unlike other diseases, do not generate great losses to aquaculture. However, the true value of neoplastic pathology compared is to better understand the histiogenesis and biological behavior of neoplasias in mammals and humans. Carcinogenesis is generally complex and in most neoplasias in both mammals and fish, the origin is unknown, and it seems that there are many factors that contribute to the onset and growth of neoplasias.
Keywords:
- Neoplasia
- diagnosis
- histopathology
- immunohistochemistry
- fish
- carcinogenesis.
How to Cite
Romano, L. A., & Pedrosa, V. F. (2020). Neoplasias in Fish: Review of the Last 20 Years. A Look from the Pathology. Annual Research & Review in Biology, 35(12), 134-153. https://doi.org/10.9734/arrb/2020/v35i1230319
References
Hajdu SI. A note from history: andmarks in history of cancer, part 1. Cancer.;117(5):1097-102.DOI: 10.1002/cncr.25553 Epub 2010 Oct 19. PMID: 20960499.
Hajdu SI. A note from history: landmarks in history of cancer, part 2. Cancer. 2011;117(12):2811-20.DOI: 10.1002/cncr.25825 Epub 2010 Dec 29. PMID: 21656759.
Willis RA. The spread of tumors in the human body. London: Butterworth & co; 1952.
Muenst S, Läubli H, Soysal SD, Zippelius A, Tzankov A, Hoeller S. The immune system and cancer evasion strategies: Therapeutic concepts. J Intern Med. 2016;279(6):541-62. DOI: 10.1111/joim.12470 Epub 2016 Jan 8. PMID: 26748421.
Abbott M, Ustoyev Y. Cancer and the immune system: The history and background of immunotherapy. Semin Oncol Nurs. 2019;35(5):150923. DOI:10.1016/j.soncn.2019.08.002 Epub 2019 Sep 13. PMID: 31526550.
Axelrod ML, Cook RS, Johnson DB, Balko JM. Biological consequences of MHC-II expression by tumor cells in cancer. Clin Cancer Res. 2019;25(8):2392-2402. DOI: 10.1158/1078-0432.CCR-18-3200 Epub 2018 Nov 21. PMID: 30463850. PMCID: PMC6467754.
Damjanov I, Linder J. Neoplasia in Anderson's Pathology. 10th ed. Published by CRC Press.1995;640- 690. ISBN 10: 0801672368.
Baranyi M, Lippai M, Szatmári Z. A stroma szerepe a tumorok kialakulásában és progressziójában [Role of the stroma in the initiation and progression of tumors]. Orv Hetil. Hungarian. 2015;156(45):1816-23. DOI: 10.1556/650.2015.30294 PMID: 26522855.
Namba M, Iijima M, Kondo T, Jahan I, Mihara K. Immortalization of normal human cells is a multistep process and a rate limiting step of neoplastic transformation of the cells. Hum Cell. 1993;6(4):253-9. PMID: 8148305.
Winquist RJ, Hall AB, Eustace BK, Furey BF. Evaluating the immortal strand hypothesis in cancer stem cells: Symmetric/self-renewal as the relevant surrogate marker of tumorigenicity. Biochem Pharmacol. 2014;91(2):129-34. DOI: 10.1016/j.bcp.2014.06.007 Epub 2014 Jun 24. PMID: 24971715.
Harshbarger JC. Activities report of the registry of tumors in lower animals, 1975 supplement. Washington, DC: Smithsonian Institution; 1976.
Effron M, Griner L, Benirschke K. Nature and rate of neoplasia found in captive wild mammals, birds and reptiles at necropsy. J Natl Cancer Inst. 1977;59(1):185-98.
Hernandez-Divers SM, Garner MM. Neoplasia of reptiles with an emphasis on lizards. Vet Clin North Am Exot Anim Pract. 2003;6(1):251-73. DOI: 10.1016/s1094-9194(02)00028-2 PMID: 12616843.
Newton AL, Lewbart GA. Invertebrate oncology: Diseases, diagnostics, and treatment. Vet Clin North Am Exot Anim Pract. 2017;20(1):1-19. DOI: 10.1016/j.cvex.2016.07.001 PMID: 27890285.
Ullrich CI, Aloni R, Saeed MEM, Ullrich W, Efferth T. Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites. Phytomedicine. 2019;64:153081. DOI: 10.1016/j.phymed.2019.153081 Epub 2019 Sep 3. PMID: 31568956.
Hason M, Bartunek P. Zebrafish models of cancer-new insights on modeling human cancer in a non-mammalian vertebrate. genes (Basel). 2019;10(11):935. DOI: 10.3390/genes10110935. PMID: 31731811. PMCID: PMC6896156.
Mawdesley- Thomas LE. Neoplasia in fish. In: Ribelin LWE, Migaki G, editors. The pathology of fishes. USA: The University of Wisconsin Press. 1975;805-870. ISBN: 0-299-06520-0.
Reichenbach-Klinke HH, Ahne W, Negele B, Ollenschlager W, Popp W, Spieser OH, Wolf K. Krankheiten und Schädigungen, 2th.ed. Gustav Fischer Verlag. Stuttgart, New York. 1980;507. ISBN: 84-200-0509-6.
Kinkelin P, Michel C, Ghittino P. Précis de pathologie des poissons. Editorial: Institut National de la Recherche. Paris: Paris Office International des Epizooties. 1985; 353. ISBN: 84-200-0686-6.
Ferguson HW. Systemic pathology of fish. A text and atlas of comparative tissue responses in diseases of teleosts. Ames, IA: Iowa State University Press. 1989;263. ISBN: 0813801478.
Stoskopf MK. Goldfish, koi, and carp neoplasia. In: Stoskopf MK, editor. Fish Medicine. London: W.B Saunders Company. 1993;490-491.
Carnevia D. Enfermedades de los peces ornamentales. Buenos aires argentina: Editorial agrovet. SA. 1993;319. ISBN: 950-9763-09-8.
Leatherland JF, Woo PTK. Fish diseases and disorders. Nosworthy Way Wallingford Oxfordshire, UK: CABI Head Office. 2010;2:403.
Roberts RJ. Neoplasia of teleosts. In: Roberts RJ, editor. Fish Pathology. 4th ed. Oxford: Blackwell Publishing Ltd. 2012;167-185.
Kalluri R. The biology and function of fibroblasts in cancer. Nat Rev Cancer. 2016;16(9):582-98. DOI: 10.1038/nrc.2016.73 PMID: 27550820.
Lyssiotis CA, Kimmelman AC. Metabolic interactions in the tumor microenvironment. Trends Cell Biol. 2017;27(11):863-875. DOI: 10.1016/j.tcb.2017.06.003 Epub 2017 Jul 19. PMID: 28734735 PMCID: PMC5814137.
Hinshaw DC, Shevde LA. The tumor microenvironment innately modulates cancer progression. Cancer Res. 2019;79(18):4557-4566. DOI: 10.1158/0008-5472. CAN-18-3962.
Baba AI, Câtoi C. Comparative oncology. Bucharest (RO): The Publishing House of the Romanian Academy; 2007. ISBN-10: 973-27-1457-3
Murphy B, Imai DM. Cutaneous Ossifying Fibroma in a Neon Tetra (Paracheirodon innesi). J Comp Pathol. 2016;155(2-3):272-275. DOI:10.1016/j.jcpa.2016.06.007 Epub 2016 Jul 27. PMID: 27476108.
Pilleri G. Uber Knochentumoren (Osteoma durum) bei Pogonias cromis Cuvier (Perciformes, Sciaenidae) von Los Cerros, Uruguay [Bone neoplasms (osteoma durum) in Pogonias cromis Cuvier (Perciformes, Sciaenidae) at Los Cerros, Uruguay]. Rev Suisse Zool, German. 1973;80(2):571-2. PMID: 4748110.
Mesbah M, Rezaie A, Tulaby Dezfuly Z. Case report of chondroma in a grass carp (Ctenopharyngodon idella). Vet Res Forum. 2016;7(2):173-6. Epub 2016 Jun 15. PMID: 27482364. PMCID: PMC4959347.
Singaravel V, Gopalakrishnan A, Raja K, Rajkumar M, Ferguson HW. Neoplasia in goldlined seabream, Rhabdosargus sarba (Forsskal, 1775). J Fish Dis. 2017;1-7. DOI: 10.1111/jfd.12737
Macintyre PA. Tumors of the thyroid gland in teleost fishes. Zool Sci Contrib N Y Zool Soc. 1960;45:161-70. PMID: 13764863.
Lombardini ED, Hard GC, Harshbarger JC. Neoplasms of the urinary tract in fish. Vet Pathol. 2014;51(5):1000-12. DOI: 10.1177/0300985813511122 Epub 2013 Dec 6. PMID: 24318975.
Lu H, Zhu G, Fan L, Zhang L. Etiology and pathology of epidermal papillomas in allogynogenetic crucian carp Carassius auratus gibelio (female) x Cyprinus carpio var. singuonensis (male). Dis Aquat Organ. 2009;83(1):77-84. DOI:10.3354/dao01985 PMID: 19301639.
Thiyagarajah A, Anderson MB, Hartley WR. Gonadal cysts in spotted gar (Lepisosteus oculatus) from Bayou Trepagnier, Louisiana, USA. Mar Environ Res. 2000;50(1-5):279-82. DOI: 10.1016/s0141-1136(00)00049-0 PMID: 11460704.
Bignold L. Principles of tumors. 1th ed. academic press. 2015;468. ISBN: 9780128015650.
Bowser PR, Casey JW, Casey RN, Quackenbush SL, Lofton L, Coll JA, Cipriano RC. Swimbladder Leiomyosarcoma in Atlantic Salmon (Salmo salar) in North America. Journal of Wildlife Diseases. 2012;48(3):795-798.
Sharon G, Benharroch D, Kachko L, Reis-Hevlin N, Zilberg D. Liposarcoma in clownfish, Amphiprion ocellaris Cuvier, produced in indoor aquaculture. J Fish Dis. 2015;38(6):575-80. DOI: 10.1111/jfd.12269 Epub 2014 Jun 11. PMID: 24917512.
Dennis MM, Diggles BK. Multicentric orocutaneous fibrosarcoma in a fork-tailed catfish (Hemiarius dioctes). Journal of Fish Diseases. 2015;38:1077-1081. DOI:10.1111/jfd.12349
Wicki G, Candarte P, Galli OM, Sal F, Luchini L, Romano LA. Alveolar rhabdomyosarcoma in the Carassius auratus (L.): Optical, immunohistochemical and ultrastructural study. Bulletin of the European Association of Fish Pathologists. 2016;36:237-245.
Ashley LM, Halver JE, Wellings SR. Case reports of three teleost neoplasms. Natl Cancer Inst Monogr. 1969;31:157-65. PMID: 4315898.
Baba AI. Neoplasm's classification in animals. Rom. Rev. Comp. One. 1999;1:36-44.
Eloy C, Ferreira L, Salgado C, Soares P, Sobrinho-Simões M. Poorly Differentiated and Undifferentiated Thyroid Carcinomas. Turk Patoloji Derg. 2015;31(Suppl1):48-59. DOI: 10.5146/tjpath.2015.01314 PMID: 26177317.
Romano LA, Tabata YA, Alexandrino AC. Histopathological and immunohistochemical diagnostic of carcinosarcoma of Mandible in a Rainbowtrout (Onchorhyincus mykiss). Acta Scientiae Veterinariae (UFRGS. Impresso). 2010;38:319-322.
Hisaoka KK. Congenital teratomata in the guppy, Lebistes reticulatus. J Morphol. 1961;109:93-113. DOI: 10.1002/jmor.1051090107 PMID: 13907766.
Newman SJ, Brown CJ, Patnaik AK. Malignant ovarian teratoma in a red-eared slider (Trachemys scripta elegans). Journal of Veterinary Diagnostic Investigation. 2003;15:77-81.
Romanucci M, Arbuatti A, Massimini M, Defourny SVP, Della Salda L. Ovarian teratoma in an adult female Zoogoneticus tequila (Webb & Miller 1998): Histological and immunohistochemical features. J Fish Dis. 2017;40(6):859-862. DOI: 10.1111/jfd.12553 Epub 2016 Sep 5. PMID: 27592861.
Ok CY, Woda B, Kurian E. Pathology of cancer. In: Pieters RS, Liebmann J, eds. Cancer Concepts: A Guidebook for the Non- Oncologist. Worcester, MA: University of Massachuset's Medical School; 2018. DOI: 10.7191/cancer_concepts.1023
Klosterhoff MC, Rodrigues RV, Sampaio LA, Pedrosa VF, Haas E, Luchini L, Wicki G, Romano LA. Occurrence of a renal lymphoma Type B in cobia, Rachycentron canadum (L). Bulletin of the European Association of Fish Pathologists. 2019;39:72-77.
Whyte RI, Donington JS. Hamartomas of the lung. Semin Thorac Cardiovasc Surg. 2003;15(3):301-4. DOI: 10.1016/s1043-0679(03)70010-0 PMID: 12973708.
Vorbach BS, Wolf JC, Yanong RP. Odontomas in two long-finned ocellaris clownfish (Amphiprion ocellaris). J Vet Diagn Invest. 2018;30(1):136-139. DOI: 10.1177/1040638717729726 Epub 2017 Sep 14. PMID: 28906183. PMCID: PMC6504150.
Litjens G, Sánchez CI, Timofeeva N, Hermsen M, Nagtegaal I, Kovacs I, Hulsbergen-van de Kaa C, Bult P, van Ginneken B, van der Laak J. Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis. Sci Rep. 2016;6:26286. DOI: 10.1038/srep26286 PMID: 27212078. PMCID: PMC4876324.
MacEwen GE, Khanna C, Radinsky R. Cancer biology and metastasis. In: Withrow SJ, MacEwen GE, editors. Small animal clinical oncology. 3th ed. Philadephia: W.B. Saunders. 2001;18-34.
Carr NJ, Bibeau F, Bradley RF, Dartigues P, Feakins RM, Geisinger KR, Gui X, Isaac S, Milione M, Misdraji J, Pai RK, Rodriguez-Justo M, Sobin LH, van Velthuysen MF, Yantiss RK. The histopathological classification, diagnosis and differential diagnosis of mucinous appendiceal neoplasms, appendiceal adenocarcinomas and pseudomyxoma peritonei. Histopathology. 2017;71(6):847-858. DOI: 10.1111/his.13324 Epub 2017 Sep 19 PMID: 28746986.
Vilalta L, Meléndez-Lazo A, Doria G, Ramis A, Solano-Gallego L, Pastor J, Martorell J. Clinical, cytological, histological and immunohistochemical features of cutaneous mast cell tumours in ferrets (Mustela putorius furo). J Comp Pathol. 2016;155(4):346-355. DOI: 10.1016/j.jcpa.2016.07.012 Epub 2016 Aug 28 PMID: 27578524.
Sirri R, Diana A, Scarpa F, Brachelente C, Vitellozzi G, Ceredi L, Mandrioli L. Ultrasonographic and pathologic study of schwannoma in a Goldfish (Carassius auratus). Vet Clin Pathol. 2015;44(4):586-91. DOI: 10.1111/vcp.12285 Epub 2015 Sep 10. PMID: 26356489.
Steinbeck RG. Pathologic mitoses and pathology of mitosis in tumorigenesis. Eur J Histochem. 2001;45(4):311-8. DOI: 10.4081/1640 PMID: 11845999.
Therman E, Kuhn EM. Mitotic modifications and aberrations in cancer. Crit Rev Oncog. 1989;1(3):293-305 PMID: 2488134.
Amend SR, Torga G, Lin KC, Kostecka LG, de Marzo A, Austin RH, Pienta KJ. Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance. Prostate. 2019;79(13):1489-1497. DOI: 10.1002/pros.23877 Epub 2019 Aug 2. PMID: 31376205. PMCID: PMC6706309.
Smolarz K, Renault T, Wolowicz M. Ultrastructural study of neoplastic cells in Macoma balthica (Bivalvia) from the Gulf of Gdansk (Poland). J Invertebr Pathol. 2006 Jun;92(2):79-84. DOI: 10.1016/j.jip.2006.04.003 PMID: 16723136.
Fukumura D, Jain RK. Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc Res. 2007 Sep-Nov;74(2-3):72-84. DOI: 10.1016/j.mvr.2007.05.003 Epub 2007 May 18. PMID: 17560615. PMCID: PMC2100036.
Klosterhoff M, Sampaio L, Okamoto M, Pedrosa V, Romano LA. Hemangioma esclerosante mandibular em Paralichthys orbignyanus: relato de caso. Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 2018;70:793-796.
Romano LA, Klosterhoff M, Führ F, Rodrigues RV, Garrido-Pereira MA, Tesser MB, Sampaio LA. Borderline ovarian mucinous cystadenoma with invasion of stroma in the goldfish Carassius auratus (L.). Bulletin of The European Association of Fish Pathologists. 2014;34:25-31.
Miyazaki T, Asai Y, Kobayashi T, Miyata M. Lympholeukemia in madai Pagrus major in Japan. Diseases of Aquatic Organisms. 2000;40(2):147-55. DOI:10.3354/dao040147
Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331(6024):1559-64. DOI: 10.1126/science.1203543 PMID: 21436443.
Chiang SP, Cabrera RM, Segall JE. Tumor cell intravasation. Am J Physiol Cell Physiol. 2016;311(1):C1-C14. DOI: 10.1152/ajpcell.00238.2015 Epub 2016 Apr 13. PMID: 27076614. PMCID: PMC4967137.
Suhail Y, Cain MP, Vanaja K, Kurywchak PA, Levchenko A, Kalluri R, Kshitiz. Systems biology of cancer metastasis. Cell Syst. 2019;9(2):109-127. DOI: 10.1016/j.cels.2019.07.003 PMID: 31465728. PMCID: PMC6716621.
Romano LA, Cuevas F. Producción Experimental de Melanomas Cutáneos en el Pez Espada Xiphophorus helleri (Heckel) y el Pez Platis, Xiphophorus Maculatus (Gunther) (Pisces Poecilidae). Revista de La Asociación de Ciencias Naturales Del Litoral. 1987;18:185-189.
Fernández AA, Bowser PR. Two cases of non-hybrid melanoma formation in Xiphophorus nezahualcoyotl Rauchenberger, Kallmann & Morizot. Journal of Fish Biology. 2008;72:292-300.
Fischer AH, Jacobson KA, Rose J, Zeller R. Hematoxylin and eosin staining of tissue and cell sections. CSH Protoc. 2008; pdb.prot4986.
Narla LD, Newman B, Spottswood SS, Narla S, Kolli R. Inflammatory pseudotumor. Radiographics. 2003;23:719-29. DOI: 10.1148/rg.233025073
Romano LA, Pedrosa VF. Re-claiming H&E: back to the future. Postgraduate Medical Journal. 2019;136955-2.
Romano LA, Marozzi AV. Epithelio-reticular cell thymoma in carp Cyprinus carpio L: A case with ultrastructural study. Journal of Fish Diseases (Print). 2004;27:369-373.
Romano LA, Klosterhoff M, Führ F, Gusmão EP, Garrido-Pereira MA, Sampaio LA, Tesser MB. Neoplasia of the sertoli cells in wild carp, Cyprinus carpio: Optical, immunohistochemical and ultrastructural study. Bulletin of The European Association of Fish Pathologists. 2013;33:84.
Romano LA, Klosterhoff M, Führ F, Garrido-Pereira MAR, Pedrosa VF. Multiple neurofibromas of the heart 1 in wild carp, Cyprinus carpio: Optical, immunohistochemical and ultrastructural study. Bulletin of The European Association of Fish Pathologists. 2015;34:201-207.
Romano LA, Wicki G, Candarte P, Galli OM, Sal F, Luchini L, Klosterhoff M, Pedrosa VF. Melanoma in a Carassius auratus (L.): Study with optical microscopy, electron microscopy and immunohistochemistry. Bull. Eur. Ass. Fish Pathol. 2018;38(6):240-248.
Romano LA, Klosterhoff MC, Medeiros AFF, Pedrosa VF. Occurrence of spontaneous melanoma in swordtail fish (Xiphophorus hellerii). Study with optical microscopy, immunohistochemistry and electron microscopy. Bull. Eur. Ass. Fish Pathol. 2020;40(4):165-172.
Rezaie A, Alishahi M, Dezfuly ZT. The first report on epicardial cavernous hemangioma in farmed sturgeon, Acipenser baerii, a microscopic survey. Iranian Journal of Fisheries Sciences. 2018;17(4):835-839. DOI: 10.22092/IJFS.2018.115482
Rahmati-Holasoo H, Soltani M, Masoudifard M, Shokrpoor S, Mirghaed AT, Ahmadpoor M. Nephroblastoma in bester sturgeon, a cultured hybrid of Huso huso × Acipenser ruthenus: Diagnostic imaging, clinical and histopathological study. J Fish Dis. 2018;1-9.
Hayashi S, Furukawa S, Abe M, Usuda K, Ogawa I, Miyamoto Y. Lymphoma in a japanese killifish. J Toxicol Pathol. 2008;21:115-117. Available:https://doi.org/10.1293/tox.21.115
Marino F, Lanteri G, Manganaro M, Macrì F. European Eel Stomatopapillomatosis in the south Tyrrhenian sea: surgical excision and post surgical recovery. Bull. Eur. Ass. Fish Pathol. 2010;30(1):30-34.
Gjurcevic E, Kužir S, Sfacteria A, Drašner K, Marino F. Spontaneous multicentric myxoma of the dermal nerve sheaths in farmed European eels Anguilla anguilla. Dis Aquat Org. 2014;111:173-176. DOI: 10.3354/dao02746
Caruso D, Keith P, Plassiart G. Skin nodular neoplasm in the armoured catfish, cascarudo (Callichthys callichthys), in French Guiana, South America. J. Appl. Ichthyol. 2003;19:126-128. Available:https://doi.org/10.1046/j.1439-0426.2003.00447.x
Lin CC, Hung SW, Tu CY, Tsou LT, Shieh MT, Lin SL, Liu PC, Wang WS. Spontaneous stomach lymphoma and liver metastases in flower horn fish, hybrid cichlid. Bulletin of European Association of Fish Pathologists. 2008; 28:115-120.
Hochwartner O, Loupal G, Wildgoose WH, Schmidt-Posthaus H. Occurrence of spontaneous tumours of the renal proximal tubules in oscars Astronotus ocellatus. Dis Aquat Org. 2010;89:185-189. DOI: 10.3354/dao02149
Rahmati-holasoo H, Hobbenaghi R, Tukmechi A Morvaridi A. The case report on squamous cell carcinoma in Oscar (Astronotus ocellatus). Comp. Clin. Pathol. 2010;19(4):421-424. DOI 10.1007/s00580-010-0963-z
Rahmati-Holasoo H, Shokrpoor S, Tavakkoli A, Vajhi A, Mousavi HE. Liposarcoma or invasive lipomatosis in flower horn fish, hybrid cichlid: Clinical, radiological, ultrasonographical and histopathological study. Journal of Fish Diseases. 2016;39:309-315. DOI:10.1111/jfd.12364
Okorie-Kanu CO, Agbakwuru IO, Nwagbara ND. Suspected Case of Rhabdomyosarcoma in a Cultured Clarias gariepinus. Nigerian Veterinary Journal. 2017;38(3).
Camus MS, Hyatt MW, Clauss TM, Berliner AL, Camus AC. Chromatophoroma in a crevice kelpfish (Gibbonsia montereyensis). Vet Clin Pathol. 2011;40(4):549-552. DOI:10.1111/j.1939-165x.2011.00365.x
Ramos P, Peleteiro MC. Três casos de neoplasias espontâneas em peixes. RPCV. 2003;98 (546):77-80.
Marino F, Licata L, Albano M, Ieni A, Caro1 GD, Macrì B. Angioleiomyoma in a conger (Conger conger). Dis Aquat Org. 2016;119:85-89. DOI: 10.3354/dao02984
Quaglio F, Zappulli V, Poppi L, Capovilla P, Capparucci F, Marino F. Squamous cell carcinoma in a wild European bullhead Cottus gobio. Dis Aquat Org. 2016;122:73-76. DOI: 10.3354/dao03065
O'Hagan BJ, Raidal SR. Surgical removal of retrobulbar hemangioma in a goldfish (Carassius auratus). Vet Clin Exot Anim. 2006;9:729-733. DOI: 10.1016/j.cvex.2006.05.028
Raidal SR, Shearer PL, Stephens F, Richardson J. Surgical removal of an ovarian tumour in a koi carp (Cyprinus carpio). Australian Veterinary Journal. 2006;84(5):178-181. Available:https://doi.org/10.1111/j.1751-0813.2006.tb12776.x
Knüsel R, Brandes K, Lechleiter S, Schmidt-Posthaus H. Two independent cases of spontaneously occurring branchioblastomas in koi carp (Cyprinus carpio). Vet. Pathol. 2007;44:237-239. DOI: 10.1354/vp.44-2-237
Sholichah L, Lusiastuti AM, Caruso D, Subamia IW, Purwaningsih U. Tumor case in koi carp (Cyprinus carpio). Indonesian Aquaculture Journal. 2010;5(2):139-145. DOI:http://dx.doi.org/10.15578/iaj.5.2. 2010
Stegeman N, Heatley JJ, Rodrigues A, Pool R. Nephroblastoma in a koi (Cyprinus carpio). Journal of Exotic Pet Medicine. 2010;19(4):298-303. Available:https://doi.org/10.1053/j.jepm.2010.10.009
Sahoo PK, Mohanty BR, Das A, Mahapatra KD, Saha JN. Cavernous haemangioma in cultured olive barb, Puntius sarana (Hamilton). Journal of Fish Diseases. 2012;35:695-697. DOI:10.1111/j.1365-2761.2012.01370.x
Marino F, Lanteri G, Rapisarda G, Perillo A, Macrì B. Spontaneous schwannoma in zebrafish, Danio rerio (Hamilton). Journal of Fish Diseases. 2012;35:239-242. DOI: 10.1111/j.1365-2761.2011.01335.x
Hyatt MW, Clauss TM, Dennison SE, Camus AC. Retroperitoneal hemangiosarcoma in a common carp Cyprinus carpio: A case report. Dis Aquat Org. 2013;107:151-160. DOI: 10.3354/dao02675
Mandrioli L, Sirri R, Gustinelli A, Quaglio F, Sarli G, Chiocchetti R. Ocular glioneuroma with medulloepitheliomatous differentiation in a goldfish (Carassius auratus). Journal of Veterinary Diagnostic Investigation. 2014;26(1):167-172. DOI: 10.1177/1040638713515218
Oryan A, Alidadi S, Shayegh H, Geramizadeh B. Cutaneous Leiomyoma in a Goldfish Carassius auratus. Fish Pathology. 2015;50 (3):112-114.
Paquette CE, Kent ML, Peterson TS, Wang R, Dashwood RH, Lohr CV. Immunohistochemical characterization of intestinal neoplasia in zebrafish Danio rerio indicates epithelial origin. Diseases of Aquatic Organisms. 2015;116(3):191-197. https://doi.org/10.3354/dao02924
Lanteri G, Ieni A, Toffan A, Abbate J, Saraò M, Barresi V, Macrì B. Immunohistochemical patterns of a non-viral papilloma in Goldfish (Carassius auratus, L.). Bull. Eur. Ass. Fish Pathol. 2016;36(5):208-213.
Rezaie A, Mousavi SM, Ansari MB. Rhabdomyosarcoma in a Silver Carp. Journal of Aquatic Animal Health. 2016;28:118-121.Hilly M, Adams ML, Nelson SC. A study of digit fusion in the mouse embryo. Clin Exp Allergy. 2002;32(4):489-98.
Shokrpoor S, Sasani F, Rahmati-Holasoo H, Zargar A. Concurrence of a fibroma ad myxoma in an oranda goldfish (Carassius auratus). Bull. Eur. Ass. Fish Pathol. 2016;36(6):263-268.
Sirri R, Pretto T, Montesi F, Berton V, Mandrioli L, Barbé T. Hikui disease in nine koi carp (Cyprinus carpio): First description of a cutaneous perivascular wall tumour. Vet Dermatol. 2016;27:301-e74. DOI: 10.1111/vde.12338
Rezaie A, Dezfuly ZT, Peyghan R. Fibrosarcoma in a Goldfish (Carassius auratus): A Case report. IJVST. 2017a;9(1):45-48. DOI: 10.22067/veterinary.v9i1.58619
Siniard WC, Sheley MF, Stevens BN, Parker-Graham CA, Roy MA, Sinnott DM, Watson KD, Marinkovich MJ, Robertson JA, Frei S, Soto E. Immunohistochemical analysis of pigment cell tumors in two cyprinid species. Journal of Veterinary Diagnostic Investigation. 2019;31(5):788-791. DOI: 10.1177/1040638719864380
Iaria C, Ieni A, Corti I, Puleio R, Brachelente C, Mazzullo G, Lanteri G. Immunohistochemical study of four fish tumors. J Aquat Anim Health. 2019;31(1):97-106. DOI: 10.1002/aah.10058 Epub 2019 Feb 5. PMID: 30554413.
Williams Jr EH, Rand TG, Bunkley-Williams L. Neurofibromas in gray snappers, Lutjanus griseus, from bermuda and the unusual distribution of nerve sheath tumors in snappers at the northern extremes of West Indian Waters. Caribbean Journal of Science. 2000;36(3-4):344-346.
Marino F, Chiofalo B, Mazzullo G, Panebianco A. Multicentric infiltrative lipoma in a farmed Mediterranean seabass Dicentrarchus labrax: A pathological and biochemical case study. Dis Aquat Organ. 2011;6;96(3):259-64. DOI: 10.3354/dao02378
Marino F, Macrì D, Lanteri G, Manganaro M, Monaco S, Germanà A. Neurofibroma in a striped mullet: Histochemical and immunohistochemical study. Journal of Aquatic Animal Health. 2010;22:92-94.
Iwanowicz LR, Goodwin AE, Harshbarger JC. Embryonal rhabdomyosarcoma of the giant gourami, Colisa fasciata (Bloch & Schneider). Journal of Fish Diseases. 2001;24:177-179. DOI: 10.1046/j.1365-2761.2001.00290.x
Lombardini ED, Law M, Lewis BS. Nephroblastoma in two siamese fighting fish Betta splendens. Fish Pathology. 2010;45(3):137-139. DOI: 10.3147/jsfp.45.137
Rahmati-Holasoo H, Alishahi M, Shokrpoor S, Jangarannejad A, Mohammadian B. Invasion of melanoma to angiolipoma in a male Siamese fighting fish, Betta splendens, Regan. Journal of Fish Diseases. 2015;38(10):925-930. DOI:10.1111/jfd.12301
Rahmati-Holasoo H, Pedram MS, Mousavi HAE, Shokrpoor S, Lewbart GA. Malignant iridophoroma in a male Siamese fighting fish (Betta splendens) Regan: A clinical, surgical and histopathological study. Bull. Eur. Ass. Fish Pathol. 2019;39(3):106-113.
Silva EG da, Gionfriddo JR, Powell CC, Campbell TW, Ehrhart EJ. Iridociliary melanoma with secondary lens luxation: Distinctive findings in a long-horned cowfish (Lactoria cornuta). Veterinary Ophthalmology. 2010;13(1):123-127. Available:https://doi.org/10.1111/j.1463-5224.2010.00804.x
Bowser PR, Abou-Madi N, Garner MM, Bartlett SL, Grimmett SG, Wooster GA, Paul TA, Casey RN, Casey JW. Fibrosarcoma in yellow perch, Perca flavescens (Mitchill). Journal of Fish Diseases. 2005;28:301-305. Available:https://doi.org/10.1111/j.1365-2761.2005.00620.x
Stefano C de, Bonfiglio R, Montalbano G, Giorgianni P, Lanteri G. Multicentric lipoma in a molly (Poecilia velifera). Bulletin European Association of Fish Pathologists. 2012;32(6):220-224.
Rahmati-holasoo H, Shokrpoor S, Enayati A, Zargar A, Ahmadpoor M. Congenital teratoma in guppy (Poecilia reticulata) in Iran. Poeciliid Research. 2014;4(1):1-5. Available:http://www.pr.bioflux.com.ro/
Rezaie A, Dezfuly ZT, Peyghan R. Occurrence of squamous cell carcinoma in a platy fish (Xiphophorus maculatus): A case report. Iranian Journal of Fisheries Sciences. 2017;16(4):1349-1353.
Lumsden JS, Marshall S. Sporadic neoplasms of farmed chinook salmon, Oncorhynchus tshawytscha (Walbaum), from New Zealand. Journal of Fish Diseases. 2003;26:393-399. DOI: 10.1046/j.1365-2761.2003.00474.x
Sirri R, Bianco C, Beraldo P, Mandrioli L, Pulvirenti I, Brachelente C, Galeotti M, Sarli G. Rhabdomyosarcoma of soft tissues in an adult brook trout (Salvelinus fontinalis). J. Comp. Path. 2015;153:190-195. Available:http://dx.doi.org/10.1016/j.jcpa.2015.05.001
Soares F, Leitão A, Moreira M, Sousa JT de, Almeida AC, Barata M, Feist SW, Pousão-Ferreira P, Ribeiro L. Sarcoma in the thymus of juvenile meagre Argyrosomus regius reared in an intensive system. Dis Aquat Org. 2012;102:119-127. DOI: 10.3354/dao02545
Marino F, Monaco S, Salvaggio A, Macrì B. Lipoma in a farmed northern bluefin tuna, Thunnus thynnus (L.). Journal of Fish Diseases. 2006;29:697-699. DOI: 10.1111/j.1365-2761.2006.00764.x
Johnston CJ, Deveney MR, Bayly T, Nowak BF. Gross and histopathological characteristics of two lipomas and a neurofibrosarcoma detected in aquacultured southern bluefin tuna, Thunnus maccoyii (Castelnau), in South Australia. Journal of Fish Diseases. 2008;31:241-247. DOI: 10.1111/j.1365-2761.2007.00863.x
Weisse C, Weber ES, Matzkin Z, Klide A. Surgical removal of a seminoma from a black sea bass. JAVMA. 2002; 221(2). DOI: 10.2460/javma.2002.221.280
Sweet M, Kirkham N, Bendall M, Currey L, Bythell J, Heupel M. Evidence of melanoma in wild marine fish populations. PLoS ONE. 2012;7(8):e41989. Available:https://doi.org/10.1371/journal.pone.0041989
Marino F, Germanà A, Panebianco A. A case of schwannoma in farmed seabream Sparus aurata. Dis Aquat Org. 2008;82:249-252. DOI: 10.3354/dao01992
Gómez S. Multiple dermal lipomas in farmed striped seabream Lithognathus mormyruson the Spanish Mediterranean coast. Dis Aquat Org. 2009;85:77-79. DOI: 10.3354/dao02062
Singaravel V, Gopalakrishnan A, Raja K, Vijayakumar R. Leiomyosarcoma in pickhandle barracuda, Sphyraena jello Cuvier, 1829. J Appl Ichthyol. 2017;33:807-809. Available:https://doi.org/10.1111/jai.13366
Willens S, Dunn JL, Frasca Jr S. Fibrosarcoma of the brood pouch in an aquarium-reared lined seahorse (Hippocampus erectus). Journal of Zoo and Wildlife Medicine. 2004;35(1):107-109. DOI: 10.1638/02-085
LePage V, Dutton, Christopher J, Kummrow M, McLelland DJ, Young K, Lumsden JS. Neoplasia of captive yellow sea horses (Hippocampus kuda) and weedy sea dragons (Phyllopteryx taeniolatus). Journal of Zoo and Wildlife Medicine. 2012;43(1):50-58. Available:https://doi.org/10.1638/2010-0236.1
Stilwell JM, Boylan SM, Howard S, Camus AC. Gas gland adenoma in a lined seahorse, Hippocampus erectus, Perry 1810. Journal of Fish Diseases. 2018;41(1):171-174. Available:https://doi.org/10.1111/jfd.12677
Lima FC, Souza APM, Mesquita EFM, Souza GN, Chinelli VCJ. Osteomas in cutlass fish, Trichiurus lepturus L, from Niteroi, Rio de Janeiro state, Brazil. J. Fish. Dis. 2002;25(1):57-61. Available:https://doi.org/10.1046/j.1365-2761.2002.00336.x
Gurcan MN, Boucheron LE, Can A, Madabhushi A, Rajpoot NM, Yener B. Histopathological image analysis: a review. IEEE Rev Biomed Eng. 2009;2:147-171. DOI:10.1109/RBME.2009.2034865
Mackay B, Osborne BM. The contribution of electron microscopy to the diagnosis of tumors. Pathobiol Annu. 1978;8:359-405. PMID: 214739.
Eyden B. Electron microscopy in tumour diagnosis: Continuing to complement other diagnostic techniques. Histopathology. 1999;35:102-108. DOI: 10.1046/j.1365-2559.1999.0741b.x
Tan HT, Low J, Lim SG, Chung MC. Serum autoantibodies as biomarkers for early cancer detection. FEBS J. 2009;276:6880-6904. DOI: 10.1111/j.1742-4658.2009.07396.x
Zhang X, Soori G, Dobleman TJ, Xiao GG. The application of monoclonal antibodies in cancer diagnosis. Expert Rev Mol Diagn. 2014;14:97-106. DOI: 10.1586/14737159.2014.866039
Zola H, Roberts TP. Monoclonal antibodies: diagnostic uses. In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester, NJ, USA; 2001. DOI:10.1002/9780470015902.a0001205.pub3
Romano LA, Marozzi V, Zenobi C.Utilizacion de anticuerpos humanos en la marcación de receptores CD3 y CD4 de linfocitos en Xiphophorus hellerii. RevSoc Científica Argent. 2004;43:123-127.
Batista RC, Figueiredo MA, Almeida DV, Romano LA, Marins LF. Impairment of the immune system in GH-overexpressing transgenic zebra fish (Danio rerio). Fish Shellfish Imm. 2014;36:519-524.
Hajdu SI. A note from history: landmarks in history of cancer, part 2. Cancer. 2011;117(12):2811-20.DOI: 10.1002/cncr.25825 Epub 2010 Dec 29. PMID: 21656759.
Willis RA. The spread of tumors in the human body. London: Butterworth & co; 1952.
Muenst S, Läubli H, Soysal SD, Zippelius A, Tzankov A, Hoeller S. The immune system and cancer evasion strategies: Therapeutic concepts. J Intern Med. 2016;279(6):541-62. DOI: 10.1111/joim.12470 Epub 2016 Jan 8. PMID: 26748421.
Abbott M, Ustoyev Y. Cancer and the immune system: The history and background of immunotherapy. Semin Oncol Nurs. 2019;35(5):150923. DOI:10.1016/j.soncn.2019.08.002 Epub 2019 Sep 13. PMID: 31526550.
Axelrod ML, Cook RS, Johnson DB, Balko JM. Biological consequences of MHC-II expression by tumor cells in cancer. Clin Cancer Res. 2019;25(8):2392-2402. DOI: 10.1158/1078-0432.CCR-18-3200 Epub 2018 Nov 21. PMID: 30463850. PMCID: PMC6467754.
Damjanov I, Linder J. Neoplasia in Anderson's Pathology. 10th ed. Published by CRC Press.1995;640- 690. ISBN 10: 0801672368.
Baranyi M, Lippai M, Szatmári Z. A stroma szerepe a tumorok kialakulásában és progressziójában [Role of the stroma in the initiation and progression of tumors]. Orv Hetil. Hungarian. 2015;156(45):1816-23. DOI: 10.1556/650.2015.30294 PMID: 26522855.
Namba M, Iijima M, Kondo T, Jahan I, Mihara K. Immortalization of normal human cells is a multistep process and a rate limiting step of neoplastic transformation of the cells. Hum Cell. 1993;6(4):253-9. PMID: 8148305.
Winquist RJ, Hall AB, Eustace BK, Furey BF. Evaluating the immortal strand hypothesis in cancer stem cells: Symmetric/self-renewal as the relevant surrogate marker of tumorigenicity. Biochem Pharmacol. 2014;91(2):129-34. DOI: 10.1016/j.bcp.2014.06.007 Epub 2014 Jun 24. PMID: 24971715.
Harshbarger JC. Activities report of the registry of tumors in lower animals, 1975 supplement. Washington, DC: Smithsonian Institution; 1976.
Effron M, Griner L, Benirschke K. Nature and rate of neoplasia found in captive wild mammals, birds and reptiles at necropsy. J Natl Cancer Inst. 1977;59(1):185-98.
Hernandez-Divers SM, Garner MM. Neoplasia of reptiles with an emphasis on lizards. Vet Clin North Am Exot Anim Pract. 2003;6(1):251-73. DOI: 10.1016/s1094-9194(02)00028-2 PMID: 12616843.
Newton AL, Lewbart GA. Invertebrate oncology: Diseases, diagnostics, and treatment. Vet Clin North Am Exot Anim Pract. 2017;20(1):1-19. DOI: 10.1016/j.cvex.2016.07.001 PMID: 27890285.
Ullrich CI, Aloni R, Saeed MEM, Ullrich W, Efferth T. Comparison between tumors in plants and human beings: Mechanisms of tumor development and therapy with secondary plant metabolites. Phytomedicine. 2019;64:153081. DOI: 10.1016/j.phymed.2019.153081 Epub 2019 Sep 3. PMID: 31568956.
Hason M, Bartunek P. Zebrafish models of cancer-new insights on modeling human cancer in a non-mammalian vertebrate. genes (Basel). 2019;10(11):935. DOI: 10.3390/genes10110935. PMID: 31731811. PMCID: PMC6896156.
Mawdesley- Thomas LE. Neoplasia in fish. In: Ribelin LWE, Migaki G, editors. The pathology of fishes. USA: The University of Wisconsin Press. 1975;805-870. ISBN: 0-299-06520-0.
Reichenbach-Klinke HH, Ahne W, Negele B, Ollenschlager W, Popp W, Spieser OH, Wolf K. Krankheiten und Schädigungen, 2th.ed. Gustav Fischer Verlag. Stuttgart, New York. 1980;507. ISBN: 84-200-0509-6.
Kinkelin P, Michel C, Ghittino P. Précis de pathologie des poissons. Editorial: Institut National de la Recherche. Paris: Paris Office International des Epizooties. 1985; 353. ISBN: 84-200-0686-6.
Ferguson HW. Systemic pathology of fish. A text and atlas of comparative tissue responses in diseases of teleosts. Ames, IA: Iowa State University Press. 1989;263. ISBN: 0813801478.
Stoskopf MK. Goldfish, koi, and carp neoplasia. In: Stoskopf MK, editor. Fish Medicine. London: W.B Saunders Company. 1993;490-491.
Carnevia D. Enfermedades de los peces ornamentales. Buenos aires argentina: Editorial agrovet. SA. 1993;319. ISBN: 950-9763-09-8.
Leatherland JF, Woo PTK. Fish diseases and disorders. Nosworthy Way Wallingford Oxfordshire, UK: CABI Head Office. 2010;2:403.
Roberts RJ. Neoplasia of teleosts. In: Roberts RJ, editor. Fish Pathology. 4th ed. Oxford: Blackwell Publishing Ltd. 2012;167-185.
Kalluri R. The biology and function of fibroblasts in cancer. Nat Rev Cancer. 2016;16(9):582-98. DOI: 10.1038/nrc.2016.73 PMID: 27550820.
Lyssiotis CA, Kimmelman AC. Metabolic interactions in the tumor microenvironment. Trends Cell Biol. 2017;27(11):863-875. DOI: 10.1016/j.tcb.2017.06.003 Epub 2017 Jul 19. PMID: 28734735 PMCID: PMC5814137.
Hinshaw DC, Shevde LA. The tumor microenvironment innately modulates cancer progression. Cancer Res. 2019;79(18):4557-4566. DOI: 10.1158/0008-5472. CAN-18-3962.
Baba AI, Câtoi C. Comparative oncology. Bucharest (RO): The Publishing House of the Romanian Academy; 2007. ISBN-10: 973-27-1457-3
Murphy B, Imai DM. Cutaneous Ossifying Fibroma in a Neon Tetra (Paracheirodon innesi). J Comp Pathol. 2016;155(2-3):272-275. DOI:10.1016/j.jcpa.2016.06.007 Epub 2016 Jul 27. PMID: 27476108.
Pilleri G. Uber Knochentumoren (Osteoma durum) bei Pogonias cromis Cuvier (Perciformes, Sciaenidae) von Los Cerros, Uruguay [Bone neoplasms (osteoma durum) in Pogonias cromis Cuvier (Perciformes, Sciaenidae) at Los Cerros, Uruguay]. Rev Suisse Zool, German. 1973;80(2):571-2. PMID: 4748110.
Mesbah M, Rezaie A, Tulaby Dezfuly Z. Case report of chondroma in a grass carp (Ctenopharyngodon idella). Vet Res Forum. 2016;7(2):173-6. Epub 2016 Jun 15. PMID: 27482364. PMCID: PMC4959347.
Singaravel V, Gopalakrishnan A, Raja K, Rajkumar M, Ferguson HW. Neoplasia in goldlined seabream, Rhabdosargus sarba (Forsskal, 1775). J Fish Dis. 2017;1-7. DOI: 10.1111/jfd.12737
Macintyre PA. Tumors of the thyroid gland in teleost fishes. Zool Sci Contrib N Y Zool Soc. 1960;45:161-70. PMID: 13764863.
Lombardini ED, Hard GC, Harshbarger JC. Neoplasms of the urinary tract in fish. Vet Pathol. 2014;51(5):1000-12. DOI: 10.1177/0300985813511122 Epub 2013 Dec 6. PMID: 24318975.
Lu H, Zhu G, Fan L, Zhang L. Etiology and pathology of epidermal papillomas in allogynogenetic crucian carp Carassius auratus gibelio (female) x Cyprinus carpio var. singuonensis (male). Dis Aquat Organ. 2009;83(1):77-84. DOI:10.3354/dao01985 PMID: 19301639.
Thiyagarajah A, Anderson MB, Hartley WR. Gonadal cysts in spotted gar (Lepisosteus oculatus) from Bayou Trepagnier, Louisiana, USA. Mar Environ Res. 2000;50(1-5):279-82. DOI: 10.1016/s0141-1136(00)00049-0 PMID: 11460704.
Bignold L. Principles of tumors. 1th ed. academic press. 2015;468. ISBN: 9780128015650.
Bowser PR, Casey JW, Casey RN, Quackenbush SL, Lofton L, Coll JA, Cipriano RC. Swimbladder Leiomyosarcoma in Atlantic Salmon (Salmo salar) in North America. Journal of Wildlife Diseases. 2012;48(3):795-798.
Sharon G, Benharroch D, Kachko L, Reis-Hevlin N, Zilberg D. Liposarcoma in clownfish, Amphiprion ocellaris Cuvier, produced in indoor aquaculture. J Fish Dis. 2015;38(6):575-80. DOI: 10.1111/jfd.12269 Epub 2014 Jun 11. PMID: 24917512.
Dennis MM, Diggles BK. Multicentric orocutaneous fibrosarcoma in a fork-tailed catfish (Hemiarius dioctes). Journal of Fish Diseases. 2015;38:1077-1081. DOI:10.1111/jfd.12349
Wicki G, Candarte P, Galli OM, Sal F, Luchini L, Romano LA. Alveolar rhabdomyosarcoma in the Carassius auratus (L.): Optical, immunohistochemical and ultrastructural study. Bulletin of the European Association of Fish Pathologists. 2016;36:237-245.
Ashley LM, Halver JE, Wellings SR. Case reports of three teleost neoplasms. Natl Cancer Inst Monogr. 1969;31:157-65. PMID: 4315898.
Baba AI. Neoplasm's classification in animals. Rom. Rev. Comp. One. 1999;1:36-44.
Eloy C, Ferreira L, Salgado C, Soares P, Sobrinho-Simões M. Poorly Differentiated and Undifferentiated Thyroid Carcinomas. Turk Patoloji Derg. 2015;31(Suppl1):48-59. DOI: 10.5146/tjpath.2015.01314 PMID: 26177317.
Romano LA, Tabata YA, Alexandrino AC. Histopathological and immunohistochemical diagnostic of carcinosarcoma of Mandible in a Rainbowtrout (Onchorhyincus mykiss). Acta Scientiae Veterinariae (UFRGS. Impresso). 2010;38:319-322.
Hisaoka KK. Congenital teratomata in the guppy, Lebistes reticulatus. J Morphol. 1961;109:93-113. DOI: 10.1002/jmor.1051090107 PMID: 13907766.
Newman SJ, Brown CJ, Patnaik AK. Malignant ovarian teratoma in a red-eared slider (Trachemys scripta elegans). Journal of Veterinary Diagnostic Investigation. 2003;15:77-81.
Romanucci M, Arbuatti A, Massimini M, Defourny SVP, Della Salda L. Ovarian teratoma in an adult female Zoogoneticus tequila (Webb & Miller 1998): Histological and immunohistochemical features. J Fish Dis. 2017;40(6):859-862. DOI: 10.1111/jfd.12553 Epub 2016 Sep 5. PMID: 27592861.
Ok CY, Woda B, Kurian E. Pathology of cancer. In: Pieters RS, Liebmann J, eds. Cancer Concepts: A Guidebook for the Non- Oncologist. Worcester, MA: University of Massachuset's Medical School; 2018. DOI: 10.7191/cancer_concepts.1023
Klosterhoff MC, Rodrigues RV, Sampaio LA, Pedrosa VF, Haas E, Luchini L, Wicki G, Romano LA. Occurrence of a renal lymphoma Type B in cobia, Rachycentron canadum (L). Bulletin of the European Association of Fish Pathologists. 2019;39:72-77.
Whyte RI, Donington JS. Hamartomas of the lung. Semin Thorac Cardiovasc Surg. 2003;15(3):301-4. DOI: 10.1016/s1043-0679(03)70010-0 PMID: 12973708.
Vorbach BS, Wolf JC, Yanong RP. Odontomas in two long-finned ocellaris clownfish (Amphiprion ocellaris). J Vet Diagn Invest. 2018;30(1):136-139. DOI: 10.1177/1040638717729726 Epub 2017 Sep 14. PMID: 28906183. PMCID: PMC6504150.
Litjens G, Sánchez CI, Timofeeva N, Hermsen M, Nagtegaal I, Kovacs I, Hulsbergen-van de Kaa C, Bult P, van Ginneken B, van der Laak J. Deep learning as a tool for increased accuracy and efficiency of histopathological diagnosis. Sci Rep. 2016;6:26286. DOI: 10.1038/srep26286 PMID: 27212078. PMCID: PMC4876324.
MacEwen GE, Khanna C, Radinsky R. Cancer biology and metastasis. In: Withrow SJ, MacEwen GE, editors. Small animal clinical oncology. 3th ed. Philadephia: W.B. Saunders. 2001;18-34.
Carr NJ, Bibeau F, Bradley RF, Dartigues P, Feakins RM, Geisinger KR, Gui X, Isaac S, Milione M, Misdraji J, Pai RK, Rodriguez-Justo M, Sobin LH, van Velthuysen MF, Yantiss RK. The histopathological classification, diagnosis and differential diagnosis of mucinous appendiceal neoplasms, appendiceal adenocarcinomas and pseudomyxoma peritonei. Histopathology. 2017;71(6):847-858. DOI: 10.1111/his.13324 Epub 2017 Sep 19 PMID: 28746986.
Vilalta L, Meléndez-Lazo A, Doria G, Ramis A, Solano-Gallego L, Pastor J, Martorell J. Clinical, cytological, histological and immunohistochemical features of cutaneous mast cell tumours in ferrets (Mustela putorius furo). J Comp Pathol. 2016;155(4):346-355. DOI: 10.1016/j.jcpa.2016.07.012 Epub 2016 Aug 28 PMID: 27578524.
Sirri R, Diana A, Scarpa F, Brachelente C, Vitellozzi G, Ceredi L, Mandrioli L. Ultrasonographic and pathologic study of schwannoma in a Goldfish (Carassius auratus). Vet Clin Pathol. 2015;44(4):586-91. DOI: 10.1111/vcp.12285 Epub 2015 Sep 10. PMID: 26356489.
Steinbeck RG. Pathologic mitoses and pathology of mitosis in tumorigenesis. Eur J Histochem. 2001;45(4):311-8. DOI: 10.4081/1640 PMID: 11845999.
Therman E, Kuhn EM. Mitotic modifications and aberrations in cancer. Crit Rev Oncog. 1989;1(3):293-305 PMID: 2488134.
Amend SR, Torga G, Lin KC, Kostecka LG, de Marzo A, Austin RH, Pienta KJ. Polyploid giant cancer cells: Unrecognized actuators of tumorigenesis, metastasis, and resistance. Prostate. 2019;79(13):1489-1497. DOI: 10.1002/pros.23877 Epub 2019 Aug 2. PMID: 31376205. PMCID: PMC6706309.
Smolarz K, Renault T, Wolowicz M. Ultrastructural study of neoplastic cells in Macoma balthica (Bivalvia) from the Gulf of Gdansk (Poland). J Invertebr Pathol. 2006 Jun;92(2):79-84. DOI: 10.1016/j.jip.2006.04.003 PMID: 16723136.
Fukumura D, Jain RK. Tumor microvasculature and microenvironment: targets for anti-angiogenesis and normalization. Microvasc Res. 2007 Sep-Nov;74(2-3):72-84. DOI: 10.1016/j.mvr.2007.05.003 Epub 2007 May 18. PMID: 17560615. PMCID: PMC2100036.
Klosterhoff M, Sampaio L, Okamoto M, Pedrosa V, Romano LA. Hemangioma esclerosante mandibular em Paralichthys orbignyanus: relato de caso. Arquivo Brasileiro de Medicina Veterinária e Zootecnia. 2018;70:793-796.
Romano LA, Klosterhoff M, Führ F, Rodrigues RV, Garrido-Pereira MA, Tesser MB, Sampaio LA. Borderline ovarian mucinous cystadenoma with invasion of stroma in the goldfish Carassius auratus (L.). Bulletin of The European Association of Fish Pathologists. 2014;34:25-31.
Miyazaki T, Asai Y, Kobayashi T, Miyata M. Lympholeukemia in madai Pagrus major in Japan. Diseases of Aquatic Organisms. 2000;40(2):147-55. DOI:10.3354/dao040147
Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science. 2011;331(6024):1559-64. DOI: 10.1126/science.1203543 PMID: 21436443.
Chiang SP, Cabrera RM, Segall JE. Tumor cell intravasation. Am J Physiol Cell Physiol. 2016;311(1):C1-C14. DOI: 10.1152/ajpcell.00238.2015 Epub 2016 Apr 13. PMID: 27076614. PMCID: PMC4967137.
Suhail Y, Cain MP, Vanaja K, Kurywchak PA, Levchenko A, Kalluri R, Kshitiz. Systems biology of cancer metastasis. Cell Syst. 2019;9(2):109-127. DOI: 10.1016/j.cels.2019.07.003 PMID: 31465728. PMCID: PMC6716621.
Romano LA, Cuevas F. Producción Experimental de Melanomas Cutáneos en el Pez Espada Xiphophorus helleri (Heckel) y el Pez Platis, Xiphophorus Maculatus (Gunther) (Pisces Poecilidae). Revista de La Asociación de Ciencias Naturales Del Litoral. 1987;18:185-189.
Fernández AA, Bowser PR. Two cases of non-hybrid melanoma formation in Xiphophorus nezahualcoyotl Rauchenberger, Kallmann & Morizot. Journal of Fish Biology. 2008;72:292-300.
Fischer AH, Jacobson KA, Rose J, Zeller R. Hematoxylin and eosin staining of tissue and cell sections. CSH Protoc. 2008; pdb.prot4986.
Narla LD, Newman B, Spottswood SS, Narla S, Kolli R. Inflammatory pseudotumor. Radiographics. 2003;23:719-29. DOI: 10.1148/rg.233025073
Romano LA, Pedrosa VF. Re-claiming H&E: back to the future. Postgraduate Medical Journal. 2019;136955-2.
Romano LA, Marozzi AV. Epithelio-reticular cell thymoma in carp Cyprinus carpio L: A case with ultrastructural study. Journal of Fish Diseases (Print). 2004;27:369-373.
Romano LA, Klosterhoff M, Führ F, Gusmão EP, Garrido-Pereira MA, Sampaio LA, Tesser MB. Neoplasia of the sertoli cells in wild carp, Cyprinus carpio: Optical, immunohistochemical and ultrastructural study. Bulletin of The European Association of Fish Pathologists. 2013;33:84.
Romano LA, Klosterhoff M, Führ F, Garrido-Pereira MAR, Pedrosa VF. Multiple neurofibromas of the heart 1 in wild carp, Cyprinus carpio: Optical, immunohistochemical and ultrastructural study. Bulletin of The European Association of Fish Pathologists. 2015;34:201-207.
Romano LA, Wicki G, Candarte P, Galli OM, Sal F, Luchini L, Klosterhoff M, Pedrosa VF. Melanoma in a Carassius auratus (L.): Study with optical microscopy, electron microscopy and immunohistochemistry. Bull. Eur. Ass. Fish Pathol. 2018;38(6):240-248.
Romano LA, Klosterhoff MC, Medeiros AFF, Pedrosa VF. Occurrence of spontaneous melanoma in swordtail fish (Xiphophorus hellerii). Study with optical microscopy, immunohistochemistry and electron microscopy. Bull. Eur. Ass. Fish Pathol. 2020;40(4):165-172.
Rezaie A, Alishahi M, Dezfuly ZT. The first report on epicardial cavernous hemangioma in farmed sturgeon, Acipenser baerii, a microscopic survey. Iranian Journal of Fisheries Sciences. 2018;17(4):835-839. DOI: 10.22092/IJFS.2018.115482
Rahmati-Holasoo H, Soltani M, Masoudifard M, Shokrpoor S, Mirghaed AT, Ahmadpoor M. Nephroblastoma in bester sturgeon, a cultured hybrid of Huso huso × Acipenser ruthenus: Diagnostic imaging, clinical and histopathological study. J Fish Dis. 2018;1-9.
Hayashi S, Furukawa S, Abe M, Usuda K, Ogawa I, Miyamoto Y. Lymphoma in a japanese killifish. J Toxicol Pathol. 2008;21:115-117. Available:https://doi.org/10.1293/tox.21.115
Marino F, Lanteri G, Manganaro M, Macrì F. European Eel Stomatopapillomatosis in the south Tyrrhenian sea: surgical excision and post surgical recovery. Bull. Eur. Ass. Fish Pathol. 2010;30(1):30-34.
Gjurcevic E, Kužir S, Sfacteria A, Drašner K, Marino F. Spontaneous multicentric myxoma of the dermal nerve sheaths in farmed European eels Anguilla anguilla. Dis Aquat Org. 2014;111:173-176. DOI: 10.3354/dao02746
Caruso D, Keith P, Plassiart G. Skin nodular neoplasm in the armoured catfish, cascarudo (Callichthys callichthys), in French Guiana, South America. J. Appl. Ichthyol. 2003;19:126-128. Available:https://doi.org/10.1046/j.1439-0426.2003.00447.x
Lin CC, Hung SW, Tu CY, Tsou LT, Shieh MT, Lin SL, Liu PC, Wang WS. Spontaneous stomach lymphoma and liver metastases in flower horn fish, hybrid cichlid. Bulletin of European Association of Fish Pathologists. 2008; 28:115-120.
Hochwartner O, Loupal G, Wildgoose WH, Schmidt-Posthaus H. Occurrence of spontaneous tumours of the renal proximal tubules in oscars Astronotus ocellatus. Dis Aquat Org. 2010;89:185-189. DOI: 10.3354/dao02149
Rahmati-holasoo H, Hobbenaghi R, Tukmechi A Morvaridi A. The case report on squamous cell carcinoma in Oscar (Astronotus ocellatus). Comp. Clin. Pathol. 2010;19(4):421-424. DOI 10.1007/s00580-010-0963-z
Rahmati-Holasoo H, Shokrpoor S, Tavakkoli A, Vajhi A, Mousavi HE. Liposarcoma or invasive lipomatosis in flower horn fish, hybrid cichlid: Clinical, radiological, ultrasonographical and histopathological study. Journal of Fish Diseases. 2016;39:309-315. DOI:10.1111/jfd.12364
Okorie-Kanu CO, Agbakwuru IO, Nwagbara ND. Suspected Case of Rhabdomyosarcoma in a Cultured Clarias gariepinus. Nigerian Veterinary Journal. 2017;38(3).
Camus MS, Hyatt MW, Clauss TM, Berliner AL, Camus AC. Chromatophoroma in a crevice kelpfish (Gibbonsia montereyensis). Vet Clin Pathol. 2011;40(4):549-552. DOI:10.1111/j.1939-165x.2011.00365.x
Ramos P, Peleteiro MC. Três casos de neoplasias espontâneas em peixes. RPCV. 2003;98 (546):77-80.
Marino F, Licata L, Albano M, Ieni A, Caro1 GD, Macrì B. Angioleiomyoma in a conger (Conger conger). Dis Aquat Org. 2016;119:85-89. DOI: 10.3354/dao02984
Quaglio F, Zappulli V, Poppi L, Capovilla P, Capparucci F, Marino F. Squamous cell carcinoma in a wild European bullhead Cottus gobio. Dis Aquat Org. 2016;122:73-76. DOI: 10.3354/dao03065
O'Hagan BJ, Raidal SR. Surgical removal of retrobulbar hemangioma in a goldfish (Carassius auratus). Vet Clin Exot Anim. 2006;9:729-733. DOI: 10.1016/j.cvex.2006.05.028
Raidal SR, Shearer PL, Stephens F, Richardson J. Surgical removal of an ovarian tumour in a koi carp (Cyprinus carpio). Australian Veterinary Journal. 2006;84(5):178-181. Available:https://doi.org/10.1111/j.1751-0813.2006.tb12776.x
Knüsel R, Brandes K, Lechleiter S, Schmidt-Posthaus H. Two independent cases of spontaneously occurring branchioblastomas in koi carp (Cyprinus carpio). Vet. Pathol. 2007;44:237-239. DOI: 10.1354/vp.44-2-237
Sholichah L, Lusiastuti AM, Caruso D, Subamia IW, Purwaningsih U. Tumor case in koi carp (Cyprinus carpio). Indonesian Aquaculture Journal. 2010;5(2):139-145. DOI:http://dx.doi.org/10.15578/iaj.5.2. 2010
Stegeman N, Heatley JJ, Rodrigues A, Pool R. Nephroblastoma in a koi (Cyprinus carpio). Journal of Exotic Pet Medicine. 2010;19(4):298-303. Available:https://doi.org/10.1053/j.jepm.2010.10.009
Sahoo PK, Mohanty BR, Das A, Mahapatra KD, Saha JN. Cavernous haemangioma in cultured olive barb, Puntius sarana (Hamilton). Journal of Fish Diseases. 2012;35:695-697. DOI:10.1111/j.1365-2761.2012.01370.x
Marino F, Lanteri G, Rapisarda G, Perillo A, Macrì B. Spontaneous schwannoma in zebrafish, Danio rerio (Hamilton). Journal of Fish Diseases. 2012;35:239-242. DOI: 10.1111/j.1365-2761.2011.01335.x
Hyatt MW, Clauss TM, Dennison SE, Camus AC. Retroperitoneal hemangiosarcoma in a common carp Cyprinus carpio: A case report. Dis Aquat Org. 2013;107:151-160. DOI: 10.3354/dao02675
Mandrioli L, Sirri R, Gustinelli A, Quaglio F, Sarli G, Chiocchetti R. Ocular glioneuroma with medulloepitheliomatous differentiation in a goldfish (Carassius auratus). Journal of Veterinary Diagnostic Investigation. 2014;26(1):167-172. DOI: 10.1177/1040638713515218
Oryan A, Alidadi S, Shayegh H, Geramizadeh B. Cutaneous Leiomyoma in a Goldfish Carassius auratus. Fish Pathology. 2015;50 (3):112-114.
Paquette CE, Kent ML, Peterson TS, Wang R, Dashwood RH, Lohr CV. Immunohistochemical characterization of intestinal neoplasia in zebrafish Danio rerio indicates epithelial origin. Diseases of Aquatic Organisms. 2015;116(3):191-197. https://doi.org/10.3354/dao02924
Lanteri G, Ieni A, Toffan A, Abbate J, Saraò M, Barresi V, Macrì B. Immunohistochemical patterns of a non-viral papilloma in Goldfish (Carassius auratus, L.). Bull. Eur. Ass. Fish Pathol. 2016;36(5):208-213.
Rezaie A, Mousavi SM, Ansari MB. Rhabdomyosarcoma in a Silver Carp. Journal of Aquatic Animal Health. 2016;28:118-121.Hilly M, Adams ML, Nelson SC. A study of digit fusion in the mouse embryo. Clin Exp Allergy. 2002;32(4):489-98.
Shokrpoor S, Sasani F, Rahmati-Holasoo H, Zargar A. Concurrence of a fibroma ad myxoma in an oranda goldfish (Carassius auratus). Bull. Eur. Ass. Fish Pathol. 2016;36(6):263-268.
Sirri R, Pretto T, Montesi F, Berton V, Mandrioli L, Barbé T. Hikui disease in nine koi carp (Cyprinus carpio): First description of a cutaneous perivascular wall tumour. Vet Dermatol. 2016;27:301-e74. DOI: 10.1111/vde.12338
Rezaie A, Dezfuly ZT, Peyghan R. Fibrosarcoma in a Goldfish (Carassius auratus): A Case report. IJVST. 2017a;9(1):45-48. DOI: 10.22067/veterinary.v9i1.58619
Siniard WC, Sheley MF, Stevens BN, Parker-Graham CA, Roy MA, Sinnott DM, Watson KD, Marinkovich MJ, Robertson JA, Frei S, Soto E. Immunohistochemical analysis of pigment cell tumors in two cyprinid species. Journal of Veterinary Diagnostic Investigation. 2019;31(5):788-791. DOI: 10.1177/1040638719864380
Iaria C, Ieni A, Corti I, Puleio R, Brachelente C, Mazzullo G, Lanteri G. Immunohistochemical study of four fish tumors. J Aquat Anim Health. 2019;31(1):97-106. DOI: 10.1002/aah.10058 Epub 2019 Feb 5. PMID: 30554413.
Williams Jr EH, Rand TG, Bunkley-Williams L. Neurofibromas in gray snappers, Lutjanus griseus, from bermuda and the unusual distribution of nerve sheath tumors in snappers at the northern extremes of West Indian Waters. Caribbean Journal of Science. 2000;36(3-4):344-346.
Marino F, Chiofalo B, Mazzullo G, Panebianco A. Multicentric infiltrative lipoma in a farmed Mediterranean seabass Dicentrarchus labrax: A pathological and biochemical case study. Dis Aquat Organ. 2011;6;96(3):259-64. DOI: 10.3354/dao02378
Marino F, Macrì D, Lanteri G, Manganaro M, Monaco S, Germanà A. Neurofibroma in a striped mullet: Histochemical and immunohistochemical study. Journal of Aquatic Animal Health. 2010;22:92-94.
Iwanowicz LR, Goodwin AE, Harshbarger JC. Embryonal rhabdomyosarcoma of the giant gourami, Colisa fasciata (Bloch & Schneider). Journal of Fish Diseases. 2001;24:177-179. DOI: 10.1046/j.1365-2761.2001.00290.x
Lombardini ED, Law M, Lewis BS. Nephroblastoma in two siamese fighting fish Betta splendens. Fish Pathology. 2010;45(3):137-139. DOI: 10.3147/jsfp.45.137
Rahmati-Holasoo H, Alishahi M, Shokrpoor S, Jangarannejad A, Mohammadian B. Invasion of melanoma to angiolipoma in a male Siamese fighting fish, Betta splendens, Regan. Journal of Fish Diseases. 2015;38(10):925-930. DOI:10.1111/jfd.12301
Rahmati-Holasoo H, Pedram MS, Mousavi HAE, Shokrpoor S, Lewbart GA. Malignant iridophoroma in a male Siamese fighting fish (Betta splendens) Regan: A clinical, surgical and histopathological study. Bull. Eur. Ass. Fish Pathol. 2019;39(3):106-113.
Silva EG da, Gionfriddo JR, Powell CC, Campbell TW, Ehrhart EJ. Iridociliary melanoma with secondary lens luxation: Distinctive findings in a long-horned cowfish (Lactoria cornuta). Veterinary Ophthalmology. 2010;13(1):123-127. Available:https://doi.org/10.1111/j.1463-5224.2010.00804.x
Bowser PR, Abou-Madi N, Garner MM, Bartlett SL, Grimmett SG, Wooster GA, Paul TA, Casey RN, Casey JW. Fibrosarcoma in yellow perch, Perca flavescens (Mitchill). Journal of Fish Diseases. 2005;28:301-305. Available:https://doi.org/10.1111/j.1365-2761.2005.00620.x
Stefano C de, Bonfiglio R, Montalbano G, Giorgianni P, Lanteri G. Multicentric lipoma in a molly (Poecilia velifera). Bulletin European Association of Fish Pathologists. 2012;32(6):220-224.
Rahmati-holasoo H, Shokrpoor S, Enayati A, Zargar A, Ahmadpoor M. Congenital teratoma in guppy (Poecilia reticulata) in Iran. Poeciliid Research. 2014;4(1):1-5. Available:http://www.pr.bioflux.com.ro/
Rezaie A, Dezfuly ZT, Peyghan R. Occurrence of squamous cell carcinoma in a platy fish (Xiphophorus maculatus): A case report. Iranian Journal of Fisheries Sciences. 2017;16(4):1349-1353.
Lumsden JS, Marshall S. Sporadic neoplasms of farmed chinook salmon, Oncorhynchus tshawytscha (Walbaum), from New Zealand. Journal of Fish Diseases. 2003;26:393-399. DOI: 10.1046/j.1365-2761.2003.00474.x
Sirri R, Bianco C, Beraldo P, Mandrioli L, Pulvirenti I, Brachelente C, Galeotti M, Sarli G. Rhabdomyosarcoma of soft tissues in an adult brook trout (Salvelinus fontinalis). J. Comp. Path. 2015;153:190-195. Available:http://dx.doi.org/10.1016/j.jcpa.2015.05.001
Soares F, Leitão A, Moreira M, Sousa JT de, Almeida AC, Barata M, Feist SW, Pousão-Ferreira P, Ribeiro L. Sarcoma in the thymus of juvenile meagre Argyrosomus regius reared in an intensive system. Dis Aquat Org. 2012;102:119-127. DOI: 10.3354/dao02545
Marino F, Monaco S, Salvaggio A, Macrì B. Lipoma in a farmed northern bluefin tuna, Thunnus thynnus (L.). Journal of Fish Diseases. 2006;29:697-699. DOI: 10.1111/j.1365-2761.2006.00764.x
Johnston CJ, Deveney MR, Bayly T, Nowak BF. Gross and histopathological characteristics of two lipomas and a neurofibrosarcoma detected in aquacultured southern bluefin tuna, Thunnus maccoyii (Castelnau), in South Australia. Journal of Fish Diseases. 2008;31:241-247. DOI: 10.1111/j.1365-2761.2007.00863.x
Weisse C, Weber ES, Matzkin Z, Klide A. Surgical removal of a seminoma from a black sea bass. JAVMA. 2002; 221(2). DOI: 10.2460/javma.2002.221.280
Sweet M, Kirkham N, Bendall M, Currey L, Bythell J, Heupel M. Evidence of melanoma in wild marine fish populations. PLoS ONE. 2012;7(8):e41989. Available:https://doi.org/10.1371/journal.pone.0041989
Marino F, Germanà A, Panebianco A. A case of schwannoma in farmed seabream Sparus aurata. Dis Aquat Org. 2008;82:249-252. DOI: 10.3354/dao01992
Gómez S. Multiple dermal lipomas in farmed striped seabream Lithognathus mormyruson the Spanish Mediterranean coast. Dis Aquat Org. 2009;85:77-79. DOI: 10.3354/dao02062
Singaravel V, Gopalakrishnan A, Raja K, Vijayakumar R. Leiomyosarcoma in pickhandle barracuda, Sphyraena jello Cuvier, 1829. J Appl Ichthyol. 2017;33:807-809. Available:https://doi.org/10.1111/jai.13366
Willens S, Dunn JL, Frasca Jr S. Fibrosarcoma of the brood pouch in an aquarium-reared lined seahorse (Hippocampus erectus). Journal of Zoo and Wildlife Medicine. 2004;35(1):107-109. DOI: 10.1638/02-085
LePage V, Dutton, Christopher J, Kummrow M, McLelland DJ, Young K, Lumsden JS. Neoplasia of captive yellow sea horses (Hippocampus kuda) and weedy sea dragons (Phyllopteryx taeniolatus). Journal of Zoo and Wildlife Medicine. 2012;43(1):50-58. Available:https://doi.org/10.1638/2010-0236.1
Stilwell JM, Boylan SM, Howard S, Camus AC. Gas gland adenoma in a lined seahorse, Hippocampus erectus, Perry 1810. Journal of Fish Diseases. 2018;41(1):171-174. Available:https://doi.org/10.1111/jfd.12677
Lima FC, Souza APM, Mesquita EFM, Souza GN, Chinelli VCJ. Osteomas in cutlass fish, Trichiurus lepturus L, from Niteroi, Rio de Janeiro state, Brazil. J. Fish. Dis. 2002;25(1):57-61. Available:https://doi.org/10.1046/j.1365-2761.2002.00336.x
Gurcan MN, Boucheron LE, Can A, Madabhushi A, Rajpoot NM, Yener B. Histopathological image analysis: a review. IEEE Rev Biomed Eng. 2009;2:147-171. DOI:10.1109/RBME.2009.2034865
Mackay B, Osborne BM. The contribution of electron microscopy to the diagnosis of tumors. Pathobiol Annu. 1978;8:359-405. PMID: 214739.
Eyden B. Electron microscopy in tumour diagnosis: Continuing to complement other diagnostic techniques. Histopathology. 1999;35:102-108. DOI: 10.1046/j.1365-2559.1999.0741b.x
Tan HT, Low J, Lim SG, Chung MC. Serum autoantibodies as biomarkers for early cancer detection. FEBS J. 2009;276:6880-6904. DOI: 10.1111/j.1742-4658.2009.07396.x
Zhang X, Soori G, Dobleman TJ, Xiao GG. The application of monoclonal antibodies in cancer diagnosis. Expert Rev Mol Diagn. 2014;14:97-106. DOI: 10.1586/14737159.2014.866039
Zola H, Roberts TP. Monoclonal antibodies: diagnostic uses. In: Encyclopedia of Life Sciences (ELS). John Wiley & Sons, Ltd: Chichester, NJ, USA; 2001. DOI:10.1002/9780470015902.a0001205.pub3
Romano LA, Marozzi V, Zenobi C.Utilizacion de anticuerpos humanos en la marcación de receptores CD3 y CD4 de linfocitos en Xiphophorus hellerii. RevSoc Científica Argent. 2004;43:123-127.
Batista RC, Figueiredo MA, Almeida DV, Romano LA, Marins LF. Impairment of the immune system in GH-overexpressing transgenic zebra fish (Danio rerio). Fish Shellfish Imm. 2014;36:519-524.
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