Derivatives of Ferulic Acid: Structure, Preparation and Biological Activities
Kehan Pei
Department of Food Science and Engineering, Jinan University, Guangzhou -510632, Guangdong, China
Juanying Ou
Food and Nutritional Science Program, School of Biological Sciences, The University of Hong Kong, Hong Kong, China
Caihuan Huang
Department of Food Science and Engineering, Jinan University, Guangzhou -510632, Guangdong, China.
Shiyi Ou *
Department of Food Science and Engineering, Jinan University, Guangzhou -510632, Guangdong, China.
*Author to whom correspondence should be addressed.
Abstract
Ferulic acid is a natural compound that possesses multiple physiological and pharmaceutical functions. The chemical, physical, and pharmaceutical properties of this phenolic acid can be improved by derivatives with other active compounds. This sentence (Hence, such improvements can widen the applications of ferulic acid in the food, cosmetic, and pharmaceutical industries.) has been deleted. This article reviewed the identification, preparation, and biological activities of feruloyl derivatives of carbohydrates, glycerol and glycerides, amide, fatty alcohol, myo-inositol, and nitric oxide. It also briefly discussed other derivatives. Researchers are encouraged to carry out toxicological, pharmacokinetic, and clinical investigation of potent active feruloyl derivatives and to develop other derivatives.
Keywords: Ferulic acid, derivatives, carbohydrates, glycerol, amide, fatty alcohol, myo-inositol.