Diversified Strains of Porcine Reproductive and Respiratory Syndrome Virus Circulating in China: A Mini-overview
Shao-Lun Zhai
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China and College of Veterinary Medicine, South China Agricultural University,Guangzhou 510642, China
Sheng-Nan Chen
Guangdong Dahuanong Animal Health Products Co., Ltd., Xinxing 527400, China.
Xiao-Hui Wen
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Dian-Hong Lv
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Zhong Huang
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
Man-Lin Luo *
College of Veterinary Medicine, South China Agricultural University,Guangzhou 510642, China.
Wen-Kang Wei
Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China.
*Author to whom correspondence should be addressed.
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) was considered as an important pathogen, which caused huge economic losses for the world swine industry annually. Until now, according to antigenic and genetic characteristics, two genotypes were identified, European (EU genotype, or type 1) genotype and North American genotype (NA genotype, or type 2), respectively. In China, both of them co-existed in swine herds, and even some novel viral strains emerged in the lastest years. The aim of the review was to describe genetic diversity of PRRSV based on non-structural protein 2 (Nsp2) in China, which could help us better understand molecular epidemiology of PRRSV. Moreover, diversified strains of PRRSV circulating in Chinese swine herds might bring serious challenges to PRRS control for government, producers and veterinary practitioners.
Keywords: Porcine reproductive and respiratory syndrome virus, multiple viral strains, European genotype, North American genotype, genetic diversity, China