Sigma Metrics of Biochemical Parameters in a Tertiary Care Hospital in Coastal Karnataka
Usha Adiga *
Department of Biochemistry, KSHEMA, Nitte University, India.
A. Preethika
Research Scholar, KSHEMA, Nitte University, India.
*Author to whom correspondence should be addressed.
Abstract
Background: Six sigma is a process of quality measurement and improvement program used in industries. Sigma metrics can be used effectively in laboratory services as total testing process has multiple steps and error can occur anywhere. The present study was undertaken to evaluate the quality of the analytical performance of clinical chemistry laboratory by calculating sigma metrics.
Methods: The study was conducted in the clinical biochemistry laboratory of Karwar Institute of Medical Sciences, Karwar. Sigma metrics of 15 parameters with automated chemistry analyzer, transasia XL 640, electrolytes with Roche electrolyte analyzer and thyroid hormones with Maglumi were analyzed.
Results: Sigma values <3 for Urea, ALT, BD, BT, Ca, creatinine (L1) and urea, AST, BD (L2), sodium, potassium and T4 were observed. Sigma lies between 3-6 for Glucose, AST, cholesterol, uric acid, total protein (L1) and ALT, cholesterol, BT, calcium, creatinine and glucose (L2), chloride, T3,TSH.Sigma was more than 6 for Triglyceride, ALP, HDL, albumin (L1) and TG, uric acid, ALP, HDL, albumin, total protein (L2).
Conclusion: Sigma metrics helps to assess analytical methodologies and augment laboratory performance. It acts as a guide for planning quality control strategy. It can be a self assessment tool regarding the functioning of clinical laboratory.
Keywords: Bias, CV%, total allowable error, sigma