Mathematical Modeling and Optimal Control of Ebola Virus Disease (EVD)

Amiru Sule *

Department of Mathematics, Zamfara State College of Education Maru, Nigeria.

Jibril Lawal

Department of Mathematical Sciences, Federal University Gusau, Nigeria.

*Author to whom correspondence should be addressed.


Abstract

In this paper, a nonlinear mathematical model is developed and analyzed to study the dynamics of Ebola virus (EVD) and the effects of some control strategies. The model validity is investigated and was found to be locally asymptotically stable when the basic reproduction number  Capture123.JPGand unstable otherwise. Pontryagin's maximum principle is applied to obtain the optimality conditions. Numerical simulation was carried out and the results obtained indicate that a combination of all three control parameters is highly effective in containing the spread of the virus.

Keywords: Ebola virus, contact tracing, personal protective equipment, optimal control.


How to Cite

Sule, Amiru, and Jibril Lawal. 2018. “Mathematical Modeling and Optimal Control of Ebola Virus Disease (EVD)”. Annual Research & Review in Biology 22 (2):1-11. https://doi.org/10.9734/ARRB/2018/32290.

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