Biosynthesis of Silver Nanoparticles Using Tradescantia zebrina aqueous Leaf Extract and Their Antibacterial Activity
Gouri Kumar Dash *
Universiti Kuala Lumpur Royal College of Medicine Perak, 30450 Ipoh, Malaysia.
Shahnaz Majeed
Universiti Kuala Lumpur Royal College of Medicine Perak, 30450 Ipoh, Malaysia.
Aisyah Shafiqah Binti Roslan
Universiti Kuala Lumpur Royal College of Medicine Perak, 30450 Ipoh, Malaysia.
*Author to whom correspondence should be addressed.
Abstract
Biologically synthesized silver nanoparticles have emerged as one of the prime areas of investigation in recent years due to their wider application in biomedical and pharmaceutical sciences. In the present paper, we report the biosynthesis of silver nanoparticles using aqueous leaf extract of T. zebrina and its antibacterial activity against common human pathogenic bacteria such as Staphylococcus epidermidis, Staphylococcus aureus, Salmonella enterica, Escherichia coli and Bacillus cereus. The antibacterial activity of the biosynthesized silver nanoparticles were compared with amikacin which was used as the positive control. The results of the study revealed good zones of inhibitions of the nanoparticles against test organisms that were comparable to amikacin and hence has a great potential in the preparation of drugs used against bacterial diseases.
Keywords: Silver nanoparticles, Tradescantia zebrina, antibacterial activity, disc diffusion method.